Stomach acid in some case secrets more than normally.İn those case stomach mucosal defense became weak ,so it can damage to the delicate mucosa and the stomach line,as well as esophagus due to reflux and may cause also duodenal ulceration,Which we known totally as Acid peptic disease.
Normally in the stomach secretes a certain amount of acid,as a natural mechanism ,which helps to digestion and assimilation of important proteins so it helps to easily absorbed by the body.
We used the term of Acid peptic disease for a conditions such as gastra-esophageal reflux disease,gastritis,gastic ulcer,duodenal ulcer and esophageal ulcer.
The common type of ulcers occur in the stomach and duodenum,which we called gastric and duodenal ulcer.
What are the symptoms of Peptic ulcer ?
most common symptoms of the peptic ulcers are ;-Abdominal pain
-Nausea
-Water brash
-Vomiting
-Loss of appetite and weight loss
-Bleeding and perforation of ulcers
We diagnosed peptic ulcer by using blood and stool tests,breat tests for bacterial infection , endoscopy and barium radiography.Endoscopy is most important tool in the diagnosis of peptic ulcer.Certain antibiotics using for the eliminate th H.pylori which most cause of infection
What are the causes of acid peptic disease ?
.Helicobacter pylori:This bacteria is responsible for 90% of all gastric and duodenal ulcers..Medication:Medication such as NSAIDS such as aspirin,diclofenac or naproxen inhibits production of these prostaglandins and it leads to ulceration and bleeding.
.Smoking,tobacco products and alcohol
.Blood group 0
.Hereditry
.Othermedication:Medications like anticoagulants,corticosteroids,chemotherapy drugs may cause ulceration
.Diet:fatty foods,coffee and poor fiber diet
.Stress:Stress can cause ulcer ,stress with smoking highly increase risk of ulceration
Symptom of the peptic ulcers
.Abdominal pain
.Nausea
.Water brash
.Vomiting loss of appetite
.Weight loss
Treatment of Acid peptic disease
Treatment of the acid peptic disease include ;
.Eradication of H.pylori: in almost all cases of peptic acid disease there infection of the H.pylori for this reason,first important to eradicate bacteria.
Anti-acid medication:İn case of extremely secretion of stomach acid, we should use medication to block acid secretion cells and increases ph of the stomach. for this purpose we will use proton pump inhibitor,omeprazol,rabeprazol and also anti-acid or H2 receptor blocker such as cimetidine,ranitidine,famotidine
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